Human ZNF837 ZNF837

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1 human znf837

1.1 gene variants
1.2 post translational
1.3 expression





human znf837

in humans, there no other aliases, , neighboring genes mir4754, a1bg, , rps5. znf837 mrna made function protein contains 1921 nucleotides, of 222-1817 translated protein containing 3 exons. protein consists of 531 amino acids weight of 58,078 da isoelectric point @ 9.525.


gene variants

there 2 transcript variants. transcript variant 1, 2050 base pairs in length, non-coding due nonsense-mediated mrna decay . transcript variant 2 made functional protein due alternate splice site


post translational

it predicted via high conservation have 4 phosphorylation sites @ t386, t455, s460, y503. internal structure includes combination of alpha helices, beta sheets , random coils.



structure of part of znf837 predicted phyre2. structure matches 99.9% confidence 37% of sequence.


expression

znf837 has observed in pancreas, liver, uterus, , muscle cells. in cases concentration low.


however, expression of znf837 seen have impact when looking @ normal vs diseased state. there consistent change able seen.








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