Homology and Evolution ZNF837



unrooted phylogenetic tree based on alignment of protein sequence of znf837 homologs.


the human znf837 has homologs present in many mammals , seen more distantly. homologs chordates. contain both cog5048 , zf-c2h2_2 domains. areas these domains found contain highest conservation rates. in humans, 5 zf-h2c2 double domains , 2 cog5048 domains present.


the protein sequence fast evolving among these homologs.



znf837 homologs percent similarity human protein graphed against date diverged homo sapiens. graphed cytochrome c, slow evolving protein, , fibrinogen, fast evolving protein, determine speed of znf837 protein s evolution


znf837 has numerous paralogs in humans, of zinc finger proteins.








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